SwissBeads simplify dilution, reduce variability by 3×, and deliver consistent antibody copy numbers — all with up to 3 months of stability
Mass cytometry is incredibly powerful — but still fundamentally relative. When you pool samples or run batches over time, the so-called batch effect blurs the line between technical variation and real biological differences.
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By calibrating your instrument to report true ion counts and antibody copy numbers, Swiss Beads™ converts your mass cytometer into a fully quantified system. This enables you to:
• Reduce inter-run marker variability 3× vs. traditional normalization
• Detect true biological change — even across days and runs
• Optimize reagent protocols by isolating instrument variability
Used in fixed whole blood, human peripheral mononuclear cells and batch-pooled experiments, Swiss Beads™ enabled marker stability with day-to-day variation as low as 2% — compared to up to 35% using standard methods.
Proprietary caibration beads are spiked into your sample
A quantification algorithm converts raw intensity to absolute ion counts
Output FCS files include true antibody copy numbers per marker
Proven on mass cytometry instruments and validated at leading immunology centers, Swiss Beads™ delivers an R² >0.99 month-to-month in elemental ion stability and enables precise comparisons across activation states and time points.
We use SCIDENTIFY tech to develop internal standards for our state-of-the-art optical process. Their ability to access information in the ion cloud is unprecedented.
SCIDENTIFYs morphological parameters enhance the accuracy of downstream clustering algorithms.
We use SCIDENTIFY services to improve our fluorescent nanoparticle product-line. They have provided us such a deep-understanding of our system. Amazing!
